Department of Veterinary Physiology and Pharmacology
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DEPARTMENT OF VETERINARY PHYSIOLOGY AND PHARMACOLOGY

 

The Department of Veterinary Physiology and Pharmacology was established in 2003.  The Department is responsible for teaching of courses in Veterinary Biochemistry, Molecular Biology, Physiology, Pharmacology, Chemotherapy, Pharmacy and Toxicology.

 

11.21.1  Postgraduate Programme

The postgraduate academic programmes of the department of Veterinary Physiology and Pharmacology are designed to offer basic and applied research training and skills to young veterinarians up to doctoral level.

The programme will provide capacity development in manpower building and career development in the specialty areas of Veterinary Physiology, Veterinary Biochemistry and Veterinary Pharmacology.

 

MASTERS’ AND DOCTORATE DEGREES CAN BE OBTAINED IN ANY OF THE FOLLOWING SPECIALIZATIONS: PHYSIOLOGY, PHARMACOLOGY AND BIOCHEMISTRY

11.21.2  Physiology Unit

MASTERS OF SCIENCE (M.Sc.) PROGRAMME IN VETERINARY PHYSIOLOGY

Admission Requirements

Master of Science in Veterinary Physiology is open to:

Graduates of Veterinary Medicine of FUNAAB and other Institutions recognized by Senate

Any other qualifications that are equivalent to FUNAAB’s DVM Degree

Graduates of Biological Sciences of FUNAAB and other Institutions recognized by Senate.

Fellows of the Nigerian Institute of Medical Laboratory Science or its equivalent.

Duration of Programme

The duration of the study for the Masters Programme shall be a minimum of four Semesters and a maximum of eight Semesters for full time candidates; while part time studies shall be for a minimum of six Semesters and a maximum of ten Semesters.


 

Graduation Requirements

The final assessment shall be undertaken only when all courses and project requirements for the degree have been fulfilled and certified by the Supervisors.

a.            Course Work

 

Candidate must have satisfactorily completed the stipulated coursework and guided study as earlier approved.  A minimum of 30 credit units is required (excluding credit units for seminars and research).  Coursework shall consist of compulsory College subjects, core departmental subjects and electives to be offered by students as advised by their Supervisory Committee.

The specialty of interest as well as specific research area shall determine the compulsory and elective courses to be offered by each student.

In addition students may be required to offer relevant courses mounted by other departments in the University.

 

First Semester Courses

Course Code

Course Title

Abbreviation

Unit

Compulsory Courses

VCM 801

Developments in Veterinary Science

DEVVETSC

1

CSC 801

Use of Computer in Research

USEOCOMP

4

VCH 803

Biostatistics in Veterinary Science

VETBIOSC

3

VPM 801

Applied Immunology

APLDIMMU

2

VCM 803

Research Ethics

RESETHIC

1

VBY 801

General Principles of Physiology

GENPHYS

3

VBY 809

Physiology Techniques and Instrumentation

PHYSTECH

2

VBY 897

Seminar I

SEMINARI

1

VBY 899

Dissertation

DISSERTN

6

Elective Courses

VBY 803

Physiology of Respiratory and Cardiovascular System

RESPCARD

3

VBY 805

Physiology of Digestion and Metabolism

PHYSDIGE

3

VBY 807

Physiology of the Rumen

RUMEPHYS

2

VBY 811

Physiology of Excretion

EXCRPHYS

3

VBY 813

Environmental Physiology

ENVIPHYS

2

 

 

 


Second Semester Courses

Course Code

Course Title

Abbreviation

Unit

Compulsory Courses

VBY 804

Physiology of Nerves and Muscle

NERVPHYS

3

VBY 806

Endocrine Physiology

ENDOPHYS

3

VBY 898

Seminar II

SEMINAII

1

Elective Coursess

VBY 802

Cell Physiology

CELLPHYS

3

VBY 808

Physiology of Steroid Hormone

STEROPHY

2

VBY 810

Enzymology

ENZYMOLO

2

VBY 812

Reproductive Physiology

REPRPHYS

2

VBY 814

Seminar III

SEMINIII

1

 

DOCTOR OF PHILOSOPHY (PH.D) PROGRAMME IN VETERINARY PHYSIOLOGY

Admission Requirements

 

To be eligible for admission to the Doctor of philosophy (Ph.D) degree Programme, a student must have obtained:

1.            A Masters degree in Physiology from FUNAAB or other Universities recognized by Senate

2.            Any other qualification adjudged to be equivalent to a Masters degree.

 

Graduation Requirements

 

a.            Course Work

Candidates must have satisfactorily completed all relevant course work at the Masters level.  Where there is a specific need, the candidate would be required to offer additional courses as required for the study.  Candidates with Masters Degree other than the field of their proposed Ph.D would be required to undertake and pass all relevant course work at the Master’s level before commencement of their Ph.D research.  Candidates should register for seminar and research as required by the Postgrdaute School.

 

b.            Seminar

Each PG student is to present at least 2 seminars viz:  a pre-data and a post-data presentation.

 

c.             Research Study and Thesis Presentation

Candidates must have satisfactorily completed the approved guided study to be eligible for the oral open defense.

 

d.            Thesis Defense

Each PG student shall openly defend his/her research thesis before a panel of appropriately constituted examiners.

 

 

 

POSTGRADUATE RESEARCH BENCHMARK

 

Doctorate Programmmes

 

a.            Minimum duration of bench/field work should be 12 months.

b.            Research should have a minimum of 5 clear objectives.

c.             Research should include a field/clinical and laboratory components.

d.            Research shall employ at least one modern laboratory technique such as molecular biology studies.

e.            Research must have the potentials of generating at least two journal publications.

 

Doctor of Philosophy (Ph.D) Course

Course Code

Course Title

Abbreviation

Unit

VBY 997

Thesis Seminar (Pre-data Seminar)

PREDATA

1

VBY 998

Thesis Seminar (Post-data Seminar)

POSTDATA

1

VBY 999

Thesis

RETHESIS

6

 

 


11.21.3  Course Synopsis Physiology Unit

 

VCM  801:  Development in Veterinary Science (1 Credit Unit)

A review of recent developments in the veterinary sciences and allied disciplines: emergent and resurgent diseases-epidemiological factors favoring emergence/recrudescence and prospects of control.  Discoveries and innovations in biomedical research; state of the art and novel research techniques and equipment.

 

CSC 801:  Use of Computers in Research (4 Credit Units)

Introduction to using computers in Research, Communication Networks; the internet and the world wide web, productivity, software Applications for Researchers; Application software, word processing, spreadsheet, database and presentation/graphics software, use of statistical packages e.g. SPSS, SAS etc and computer programming.

 

VCH 803:  Biostatistics in Veterinary Science (2 Credit Units)

Development of sampling protocols in Veterinary Research, sampling survey methods, sampling frames, sampling design sampling methods and sampling size determination.  Development of data management protocol, data collection instruments, data organization, analysis and archiving.  Health demographic surveys.

 

VPM 801:  Applied Immunology (2 Credit Units)

Introduction/Concepts, Types of immunity, Antigens and immune responses, Immunoglobulins, Mechanisms of specific and non specific immune responses, Chemical mediators of immune responses complement systems, lymphoid system, Cells of the immune system, Antibody mediated allergic reactions, Cell mediated immunological reactions, Delayed hypersensitivity reactions, Autoimmune reaction, Immunological tolerance, Major histocompatibility complex, gene regulation of immune responses, Oncogenesis and differentiation antigens, Immunodeficiences, Immunity to parasitic and microbial (viruses bacteria and fungi) infections, Antigen and antibody reactions in vitro.

 

VCM 803:  Research Ethics (1 Credit Unit)

Principles of research integrity, responsible conduct of research, animal welfare and ethics are to be discussed.

 

VBY 801: General Principles of Physiology (3 Credit units)

Functional organization of the living body.  Homeostasis, pH of body fluids and its regulation.  Buffer systems, acidosis and alkalosis, role of the kidneys and respiratory system in body fluid.  Body temperature, its regulation and fever.  Radiation, its uses and hazards in biology.  Body defences mechanism, innate and adoptive immune response.  Reticulo-endothelial system and properties of lumphocytes.

 

VBY 802: Cell Physiology (3 Credit units)

Structures and functions of bone,  Functions of lysosomes, reticulum, Golgi apparatus, mitochondria and nucleus.  Cell locomotion, Cell cycle: mitotic processes and replication of chromosomes and DNA, tRNA, rRNA, process of translation marrow will be a major focus.  The site of production, structure, function, metabolism and kinetics of blood cells, (red blood cells, white blood cells, thrombocytes) will also be considered in detail.  Organization of cell membrane, cytoplasm, organelles and nucleus.  Comparison of various cell types, blood cell, muscle cell, nerve cell, bone cell, liver cell, plant cell and specialized cells.  Physiology of the cell: and protein synthesis on ribosomes.  Introduction to genetic engineering.  Transport through cell membrane.  Diffusion through lipid bilayer and protein channels.  Selective permeability, factors affecting transport across cell membrane.  Osmolarity, active transport, sodium potassium pump.  Membrane potential and action potential.  Endocytosis: phagocytosis and pinocytosis.  Control of activities in the cell: genetic regulation and enzymatic regulation of cell activities.

 

VBY 803: Physiology of Respiratory and Cardiovascular Systems  (3 Credit units)

Major aspects of cardiac physiology and cardiovascular functions, current techniques for respiration.  Also to be considered in details in this course are the following topics:  Physiology of respiration, pulmonary ventilation, pulmonary volumes and capacities, physical principle of gaseous exchange, transport of oxygen and carbon dioxide in the blood.  Regulation of respiration, neural control of respiratory cycle, anoxia, effect of breathing on circulation.  Heart muscle, its rhythmic excitation and physiology.


 

VBY 804: Physiology of Nerves and Muscle (3 Credit units)

Central and autonomic nervous systems, with emphasis on: different signals from the viscera, resting membrane potential of nerves, nerve action potential and its propagation.  Metabolism of the nervous system, spinal cord, effect of section of roots of spinal nerves, properties of spinal reflexes.  Brain; reticular formation of brain, the thalamus, functions of cerebral hemisphere.  Physiology of muscular system, molecular mechanism of muscle contraction, special features of muscle and abnormality of skeletal muscle function.

 

VBY 805: Physiology of Digestion and Metabolism (3 Credit units)

Functional anatomy of the digestive system.  Structure of salivary glands, regulation of salivary secretion, composition of saliva and its significance to digestion.  Food digestion in the stomach:  structure of gastric glands, secretion and regulation of gastric juice.  Enzymic digestion of food, stomach movements and their control.  Structure of the intestinal glands: secretion, regulation and composition of intestinal juice.  Bile: synthesis, storage and release, its regulation of release.  Pancreatic juice: storage, release and its regulation by hormones of the gastro-intestinal tract (GIT), and their significance in digestion.  Digestion of food in the small intestine, structure of absorptive surfaces and the villi.  Nutrient absorption from the GIT, mechanism of absorption.

 

VBY 806: Endocrine Physiology                 (3 Credit units)

The correlation between the structure and function of organs of the endocrine system.  The main focus of the course will be on;  Historical background, synthesis, release and mechanism of action of the various hormones from the pituitary, pancreas, adrenal, thyroid and parathyroid glands; including their methods of extraction, bioassay, radioimmunoassay and other assay techniques.  Types of chemical messengers.  Neuroendocrine integration; Influence of the nervous system on endocrine glands and pathways involved in regulation of endocrine activity.

 

VBY 807: Physiology of the Rumen (2 Credit units)

Structure of the rumen, development of ruminant stomach.  Salivary glands and their secretions.  Saliva composition and its role in rumen fermentation, regulation and salivary secretion.  Significance of oesophageal groove.  Eructation, causes, prevention and cure of bloat.  Rumen micro flora and fauna, rate of microbial symbiosis.  Quantitative aspects of rumen gases and VFA production.  Absorption of VFA and nitrogenous compounds and lipids.  Vitamin and mineral metabolism.  Absorption from the omasum and abomasums.  Digestion and absorption in the small intestine and hindgut.


VBY 808: Physiology of Steroid Hormones (2 Credit units)

The development, the structure and function of the male and female reproductive hormonal system, including hormones pregnancy, parturition and lactation.  Adrenal cortex, corticosteroids, mineralocorticoids and glucocorticoids synthesis and biological actions of corticoids, regulation of adrenocortical secretion, effects of adrenalectomy.  Stress mechanism and general adaptation syndromes.  Relationship of steroids to metabolic diseases.

 

VBY 809: Physiology Techniques and Instrumentation   (2 Credit units)

The characteristics, application and limitations of equipment used in modern physiology.  Each student must be able to demonstrate competence in the use of all the available equipment including computers.  The course will also include; practical exercises with theoretical introduction in the following areas; anesthesia, (local and general), in different animals.  Blood and plasma estimation, measurement of blood pressure by direct and indirect methods.  Blood grouping, Blood pressure and flow rates etc.  Electroencephalograph. Use of colorimeters and spectrophotometer:  Analysis of blood, urine and other body fluids.  Chromatographic analysis.  Surgical techniques used in physiological research.  Ablation and replacement therapy.  Electrophoresis and PCR techniques.

 

VBY 810: Enzymology (2 Credit units)

Enzymes:  their structures and functions, classification, nomenclature, and specificity.  Enzymes and homeostasis.  Regulation of enzyme-catalysed reactions.  Co-enzymes and co-factors, allosteric enzymes, isoenzymes, biological oxidation  enzyme kinetics.  Uses of enzymes for correlation of metabolic disorders, use of enzymes as biological markers.

 

VBY 811: Physiology of Excretion (3 Credit units)

Renal physiochemical aspects involved in excretory secretory and endocrine functions of the kidney.  The transmission of blood gases, and the buffer system in the blood.  Physiologic anatomy of the kidney, basic theory of nephron function.  Renal blood flow, glomerular filtration rate. Urine formation by the kidney, tubular function and plasma clearance.  Reabsorption and secretion in the kidney, inulin and creatinine clearance as measure of G.F.R.  Paramino-hippuric acid (PAH) as a measure of plasma flow.  Urine constituents and renal mechanism for the control of glomerular filtration, excretion of urea, sodium and potassium, regulation of blood volume, and composition of extracellular fluid.   Thirst mechanism and regulation of acid-base balance.  Micturition, physiologic anatomy of sweat glands, secretion and its regulation by the autonomic nervous system.  Mechanism of sweat secretion.  Acclimatization of sweat mechanism, factors influencing sweating.


 

VBY 812: Reproductive Physiology (2 Credit units)

Development of the reproductive system, hypothalamopituitary control of reproduction, ovarian follicle development, ovulation corpus luteum development and ovarian cycles, puberty and reproductive senescence, sexual behavior and external factors controlling reproductive cycle.  Pregnancy, development of the embryo and parturition: the mammary gland, lactogenesis diseases associated with the mammary gland; Male reproductive cycle, spermatogenesis, puberty and anabolic steroids, clinical correlations. 

 

VBY 813: Environmental Physiology (2 Credit units)

Environment Systems, Nature and levels of adaptation and mechanisms of adaptation, Osmoregulation, Energy supply: Energy budgets in animals inhabiting different environments, Respiratory and circulatory adaptation, Temperature and its effects, Coping with different environments, Environmental Chemistry, Environmental Health, Different types of habitats (Extreme terrestrial habitat, deserts, very cold habitats, high altitude habitat), The Nature and Levels of Adaptation, Water Quality Management, Air Quality Management, Environmental Toxicology, Risk Assessment and Management.

 

VBY 814: Seminar III  (1 Credit unit)

Each student will be required to write a literature review on one topic that is related to his/her project and the title must be approved by the Supervisor and presented at Seminar.

 

VBY 897: Thesis seminar 1 (Pre-data Seminar)  (1 Credit unit)

This is essentially a pre-data seminar on the research focus of the student’s project covering the title, objective and scope of the work, review of relevant literature, experimental design and methodology.

 

VBY 898: Thesis seminar II (Post-data Seminar) (1 Credit unit)

This is a follow-up seminar/post-data or bench work findings.  It should cover research findings, detailed analysis and interpretation of research results, discussion of findings in view of previous reports and new ideas emanating from the study, conclusion and recommendations for future work.

 

VBY 899:  Approved Research Project Dissertation (6 Credit units)

This course will take into account the broad areas of specialization of each candidate and will be taken into consideration in the choice of the projects.


11.21.4  Postgraduate Lecturers Physiology Unit

S/N

Staff Name

Rank

Qualifications

Specialty

1

Durotoye, L. A.

Senior Lecturer /

Head of Department

DVM, M.Sc, Ph.D 

Veterinary Endocrinology, Reproduction, Haematology

2

*Olayemi F. O.

Professor

DVM, M.Sc, Ph.D  FCVSN

Veterinary Endocrinology, and Reproduction

3

*Oyewale O. J.

Professor

DVM, M.Sc, Ph.D  FCVSN

Veterinary Haematology, Gastroenterology

4

Ajibola, E.S.

Lecturer I

DVM, M.Sc

Cardiovascular and Nervous system

5

Adeleye, O.E.

Lecturer I

DVM, M.Sc

Renal, Reproduction Nerve and Muscle Physiology

 

* Associate Lecturers


11.21.5  Pharmacology Unit

MASTERS OF SCIENCE (M.Sc.) PROGRAMME IN VETERINARY PHARMACOLOGY

Admission Requirements

Master of Science in Veterinary Pharmacology is open to:

Graduates of Veterinary Medicine of FUNAAB and other Institutions recognized by Senate

Any other qualifications that are equivalent to FUNAAB’s DVM Degree

Graduates of Biological Sciences of FUNAAB and other Institutions recognized by Senate.

Fellows of the Nigerian Institute of Medical Laboratory Science or its equivalent.

 

Duration of Programme

The duration of the study for the Masters Programme shall be a minimum of four Semesters and a maximum of eight Semesters for full time candidates; while part time studies shall be for a minimum of six Semesters and a maximum of ten Semesters.

Graduation Requirements

The final assessment shall be undertaken only when all courses and project requirements for the degree have been fulfilled and certified by the Supervisors.

 

a.            Course Work

 

Candidate must have satisfactorily completed the stipulated coursework and guided study as earlier approved.  A minimum of 30 credit units is required (excluding credit units for seminars and research).  Coursework shall consist of compulsory College subjects, core departmental subjects and electives to be offered by students as advised by their Supervisory Committee.

 

The specialty of interest as well as specific research area shall determine the compulsory and elective courses to be offered by each student.

 

In addition candidates may be required to offer relevant courses mounted by other departments in the University.


First Semester Courses

Course Code

Course Title

Abbreviation

Unit

Compulsory Courses

VCM 801

Developments in Veterinary Science

DEVVETSC

1

CSC 801

Use of Computer in Research

USEOCOMP

4

VCH 803

Biostatistics in Veterinary Science

VETBIOSC

3

VPM 801

Applied Immunology

APLDIMMU

2

VCM 803

Research Ethics

RESETHIC

1

VPC 801

Pharmacodynamics and Pharmacokinetics

PHARKOLKC

3

VPC 811

Experimental Techniques

EXPTECHN

2

VPC 813

Research grant writing and article publication

RESGRANT

2

VPC 897

Seminar I

SEMINARI

1

VPC 899

Dissertation

DISSERTN

6

Elective Courses

VPC 803

Cardiovascular Pharmacology

CARDIPHA

3

VPC 805

Endocrine and Reproductive Pharmacology

ENDOPHAM

3

VPC 807

Neuropharmacology and Inflammation

NEUROPHA

3

VPC 809

Ethno – Pharmacology

ETHNOPHA

3

*BCH  811

Methods of Biochemical Analysis 

METHBCHA

4

 

Second Semester Courses

Course Code

Course Title

Abbreviation

Unit

Compulsory Courses

VPC 812

Special Problems in Pharmacology

SPECPHAM

2

VPC 814

Seminar

SEMINAR

1

VPC 898

Seminar II

SEMINAII

1

Elective Courses

VPC 802

Gastrointestinal Pharmacology

GASTPHAM

3

VPC 804

Renal and Electrolyte Pharmacology

RENPHARM

2

VPC 806

Immunopharmacology and Inflammation

IMMUPHAR

3

VPC 808

Chemotherapy

CHEMTHER

3

VPC 810

Advanced Toxicology

ADVANTOX

3

*             Outside course mounted in COLBIOS

 

DOCTOR OF PHILOSOPHY (PH.D) PROGRAMME IN VETERINARY PHARMACOLOGY

Admission Requirements

To be eligible for admission to the Doctor of philosophy (Ph.D) degree Programme, a student must have obtained:

1.            A Masters degree from FUNAAB or other Universities recognized by Senate

2.            Any other qualification adjudged to be equivalent to a Masters degree

Graduation Requirements

a.            Course Work

Candidates must have satisfactorily completed all relevant course work at the Masters level.  Where there is a specific need, the candidate would be required to offer additional courses as required for the study.  Candidates with Master’s Degree other than the field of their proposed Ph.D would be required to undertake and pass all relevant course work at the Master’s level before commencement of their Ph.D research.  Candidates should register for seminar and research as required by the Postgraduate School.

 

b.            Seminar

Each PG student is to present at least 2 seminars viz:  a pre-data and a post-data presentation.

 

c.             Research Study and Thesis Presentation

Candidates must have satisfactorily completed the approved guided study to

 

d.            Thesis Defense

Each PG student shall openly defend his/her research thesis before a panel of appropriately constituted examiners.

 

 

POSTGRADUATE RESEARCH BENCHMARK

 

Doctorate Programmmes

 

a.            Minimum duration of bench/field work should be 12 months.

b.            Research should have clear objectives.

c.             Research should include a field/clinical and laboratory components.

d.            Research shall employ at least one modern laboratory technique such as molecular biology studies.

 


 

Doctor of Philosophy (Ph.D) Course

Course Code

Course Title

Abbreviation

Unit

VPC 997

Thesis Seminar (Pre-data Seminar)

PREDATA

1

VPC 998

Thesis Seminar (Post-data Seminar)

POSTDATA

1

VPC 999

Thesis

RETHESIS

6

 

11.21.6  Course Synopsis Pharmacology Unit

VCM 801:  Development in Veterinary Science (1 Credit Unit)

Recent developments in the veterinary sciences and allied disciplines: emergent and resurgent diseases, epidemiological factors favoring emergence/recrudescence and prospects of control.  Discoveries and innovations in biomedical research; state of the art and novel research techniques and equipment.

CSC 801:  Use of Computers in Research (4 Credit Units)

Introduction to using computers in Research, Communication Networks; the internet and the World Wide Web, productivity, Software Applications for Researchers; Application Software, Word Processing, Spreadsheet, Database and Presentation/graphics software, use of statistical packages e.g. SPSS, SAS etc and Computer Programming.

 

VCH 803:  Biostatistics in Veterinary Science (3 Credit Units)

Development of sampling protocols in Veterinary Research sampling survey methods, sampling frames, sampling design, sampling methods and sampling size determination.  Development of data management protocol, data collection instruments, data organization, analysis and archiving.  Health demographic surveys.

 

VPM 805:  Advanced Immunology (2 Credit Units)

Introduction/Concepts, Types of immunity, Antigens and immune responses, Immunoglobulins, Mechanisms of specific and non specific immune responses, Chemical mediators of immune responses complement systems, Lymphoid system, Cells of the immune system, Antibody mediated allergic reactions, Cell mediated immunological reactions, Delayed hypersensitivity reactions, Autoimmune reaction, Immunological tolerance, Major histocompatibility complex, Gene regulation of immune responses, Oncogenesis and differentiation antigens, Immunodeficiences, Immunity to parasitic and microbial (viruses bacteria and fungi) infections, Antigen and antibody reactions in vitro.

 

VCM 803:  Research Ethics (1 Credit Unit)

Principles of research integrity, responsible conduct of research, animal welfare and ethics.

 

VPC 801: Pharmacodynamics and Pharmacokinetics  (3 Credit Units)

The dynamics of drug absorption, distribution and elimination. The physicochemical factors in transfer of drugs across membranes e.g. electrolytes and influence of pH.  Factors that modify absorption, bioavailability, routes of administration and drug distribution e.g. distribution to the CNS, Redistribution and placental transfer.  Drug biotransformation, factors that modify drug biotransformation, biotransformation in fetus and neonates, biotranformation in elderly, biotransformation and drug toxicity.  Excretion of drugs, renal excretion, biliary and fecal excretion, excretion by other routes.

Pharmodynamics: Mechanism of drug action and relationship between drug concentration and effects, drug receptors and cellular sites of drug action.

 

VPC 802: Gastrointestinal Pharmacology (3 Credit Units)

The digestive system; agents for control of gastric acidity and treatment of peptic ulcers, agents affecting gastrointestinal water flux and motility, digestants and bile acids.

 

VPC 803: Cardiovascular Pharmacology (3 Credit Units)

The pharmacology of the cardiovascular system: cardiac glycoside, antiarrythmics, antihypertensives, vasodilators and antilipemic agents.  Drugs acting on the blood and the blood forming organs.

 

VPC 804: Renal and Electrolyte Pharmacology (3 Credit Units)

The pharmacology of the renal system:  diuretics and other agents employed in the mobilization of oedema fluid, agents affecting the renal conservation of water, inhibitors of tubular transport of organic compounds.  Water, salts and ions; agents affecting volume and composition of body fluids.

 

VPC 805: Endocrine and Reproductive Pharmacology (3 Credit Units)

The pharmacology of the endocrine and reproductive system: Adenophyphyseal hormones and related substances, thyroid and antithyroids drugs, adrenocortical hormone, Insulin, oral hypoglycemic agents and the pharmacology of endocrine pancreas.  Estrogens, progestins, androgens and drugs affecting uterine motility.

 

VPC 806: Immunopharmacology and Inflammation  (3 Credit Units)

The immunomodulating agents, uses and limitations of immunosuppressive agents, cyclosporine, cytotoxic agents, antibodies and other immunosuppressive agents like adrenocorticoids, sulfasalazine, FK-506, methoxsalen and thalidomide.  Drug therapy of inflammation.

 

VPC 807: Neuropharmacology (3 Credit Units)

Neuro humoral transmission:  the autonomic and somatic motor nervous systems: Cholinergic agonists, anticholinesterase agents, atropine, scopolamine and related antimuscarinic drugs. Agents acting at the neuromuscular junction and autonomic ganglia.  Cathecolamines and symphatomimetic drugs, adrenergic receptors antagonists.

Drugs acting on CNS:  History and principles of anaesthesiology, general anaesthetics, local anaesthetics, therapeutic gases (oxygen, carbon dioxide,  Helium and water vapour). Hypnotics and sedatives, Opiod analgesics and antagonists.

 

VPC 808: Chemotherapy (3 Credit Units)

Chemotherapy of Parasitic infections e.g. antihelmintics, antiprotozoal against trypanosomiasis, babesiosis, erlichiosis and other protozoal  infections.  Chemotherapy of microbial diseases e.g. sulphonamides, quinolones, Penicillins, cephalosporins, and other Beta-lactam antibiotics, aminoglycosides, tetracyclines, chloramphenicol, erythromycin, antifungal agents, antiviral agents and antineoplastic agents.

 

VPC 809: Ethno-Pharmacology (3 Credit Units)

The commonly used medicinal plants in the managements of some common disease conditions of man and animals in Nigeria e.g. Vernonia amydalina, Ocimum gratissimum, Moringa morindoides,  Aloe-vera and other medicinal plants.

 

VPC 810: Advanced Toxicology (3 Credit Units)

Absorption, distribution, metabolism and excretion of toxins, factors affecting the activity of toxicants, diagnosis and antidotal therapy.  Algae poisoning, cyanide poisoning, food hazards, herbicide poisoning, mycotoxicoses, ionophone toxicity, insecticide and acaricides toxicity, industrial toxicants, metals and micronutrients poisoning, plants and fungi poisoning, Redenticides and strychnine poisoning and venomous organisms.

 

VPC 811: Experimental Techniques (2 Credit Units)

Principles and use of common research and experimental techniques in pharmacology/toxicology, including chromatography, electrophoresis, spectrometry, tissue culture, western blot and PCR.

 


VPC 812: Special Problems in Pharmacology (2 Credit Units)

Independent study and discussion of current topics in Pharmacology/Toxicology.

 

VPC 813: Research Grant Writing and Article publication (2 Credit Units)

Proposal writing for grants, students will write a minimum of one proposal per semester; training on paper writing involving the student criticizing one journal article from the area of study and writing one article per semester.

 

*BCH 811: Methods of Biochemical Analysis (4 Credit Units)

Review of basic techniques:  Buffers and pH. Tissue preparations and cell culture. Principles of centrifugation. Preparation of subcellular organelles.  Use of marker enzymes.

Spectrophotometry and fluorometry. UV and IR spectrophotometry. Flourescene and Photophorescene. Chromatographic purification of proteins and amino acids.  Ion exchange,  molecular sieving, affinity chromatography, Partition chromatography. Chromatographic separation of Lipids (thin-layer, column, gas-liquids chromatographic techniques etc). Electrophoresis – preparative and analytical.

Special techniques:  Viscometry, X-ray diffraction, Circular Dichroism (C.D) and Optical Rotatory Dispersion (O.R.D) Magnetic Resonance Methods.  Application of Radio labels in Biochemistry.

Clinical Biochemistry approaches -  Physiological Methods in Health and Disease.  Techniques in Nutrition Studies – Analysis of mycotoxin, pesticides and Environmental contaminants.  Emerging techniques in Biochemistry – recent research application of some techniques may be mounted.

 

VPC 814: Seminar (1 Credit Unit)

Student will be required to present a seminar on a topic in the area of pharmacology or toxicology.

 

VPC 897: Thesis Seminar I (Pre-data Seminar)  (1 Credit unit)

This is essentially a pre-data seminar on the research focus of the student’s projects covering the title, objective and scope of the work, review of relevant literature, experimental design and methodology.

 

VPC 898: Thesis Seminar II (Post-data Seminar)                 (1 Credit Unit)

This is a follow-up seminar/post-data or bench work findings.  It should cover research findings, detailed analysis and interpretation of research results, discussion of findings in view of previous reports and new ideas emanating from the study, conclusion ad recommendations for future work.

 

VPC 899: Dissertation (6 Credit units)

Original and independent research project in Pharmacology / Toxicology taken into consideration the area of specialization of the candidate in the choice of topics for the projects.

 

11.21.7  Postgraduate Lecturers Pharmacology Unit

S/N

Staff Name

Rank

Qualifications

Specialty

1

Arowolo R.O.A

Professor

DVM, M.Sc, Ph.D FCVSN

Veterinary Pharmacology and Toxicology

2

* Abatan, M. O.

Professor

DVM, M.Sc, Ph.D FCVSN

Veterinary Pharmacology and Toxicology

3

* Saba A. B.

Senior Lecturer

DVM, M.Sc, Ph.D

Veterinary Pharmacology

4

Olukunle, J.O.

Senior Lecturer

DVM, M.Sc, Ph.D FCVSN

Veterinary Pharmacology and Toxicology

5

Adenubi, O.T

Lecturer I

DVM, M.Sc,

Veterinary Pharmacology and Toxicology

6

Oyewusi J.A.

Adjunct Lecturer

DVM, M.Sc

Veterinary Pharmacology and Toxicology

 

 


 

11.22     PROFESSIONAL MATSTER’S DEGREE PROGRAMME IN VETERINARY PHARMACY AND THERAPEUTICS

Degree Awarded:  Professional Masters of Veterinary Pharmacy and Therapeutics (MVPT)

Admission Requirements

DVM or equivalent degree e.g. B.Vet from accredited institutions with VCN registration will be admitted to this program. Preference will be given to those who are currently employed in a relevant academic, government, or industrial position.

Duration of programme

The Professional Masters degree programme shall be a minimum of three Semesters and a maximum of five Semesters for full time candidates; while part time studies shall be for a minimum of five Semesters and a maximum of seven Semesters

 

Graduation Requirements

The final assessment shall be undertaken only when all courses and project requirements for the degree have been fulfilled and certified by the Supervisors and the Head of Department.

 

Graduation Requirement

This is a three – five semesters programme involving basic and practical training in veterinary drugs manufacturing and veterinary drugs marketing in use.

The course is made up of lecturers, tutorials, laboratory classes, clinics and field trip in the first two semesters and a project work and externship in the third semester.

The programme will run on part-time basis with classes on Fridays and Saturdays.

Candidates for the programme must satisfy the following requirements;

Successful completion of prescribed course work of minimum of 22 credit units

Successful completion of approved project work and externship shall be required to qualify for the award of Professional Masters in Veterinary Pharmacology and Therapeutics.


 

Program Description for MVPT

This programme is designed to provide higher professional training requirements for graduates of DVM or its equivalent degree, who may want to acquire professional postgraduate training in veterinary pharmacy, pharmacology and therapeutics.

 

This is especially valuable for those working or contemplating to work in veterinary drugs manufacturing or veterinary drugs marketing industry.

 

Upon completing this course, students would have obtained knowledge and skills that can positively impact professional healthcare sector, veterinary and economic outcomes by applying their drug knowledge resources to veterinary situations.

 

This course will provide valuable instruction on the uses and indications of veterinary labeled medications used in the treatment of diseases affecting animal patients.  Common animal disease states affecting small animals, large animals, food animals and other animal patients will be presented and discussed.  Requirements for compounding drugs of veterinary importance; methods of drug discovery;  drug production; drug development and clinical trials sourcing and marketing of veterinary drugs and biologicals (locally and internationally) will be discussed.  Legal and regulatory issues that affect the practice of veterinary pharmacy in Nigeria will be emphasized.  Exploration and utilization of field cases, clinical cases, text and internet-based veterinary – specific resources will be highlighted.  Additionally, current topics in veterinary therapeutics and veterinary pharmacy will be discussed.

 

Course Structure

First Semester Courses

Course Code

Course Title

Abbreviation

Unit

Compulsory Courses

MPT 801

Clinical Pharmacology

CLINPHAR

3

MPT 803

Veterinary Therapeutics

VETTHERA

2

MPT 805

Clinical Veterinary Pharmacy II

CLIVETPH

3

MPT 807

Applied Biostatistics in Vet. Science

APPBIOVE

2

MPT 889

Project

PROJECT

6

Elective Courses

CSC 801

Use of Computer in Research

USEOCOMP

4

 


Second Semester Courses

Course Code

Course Title

Abbreviation

Unit

Compulsory Courses

MPT 802

Veterinary Pharmaceutics

VETEPHAR

2

MPT 804

 Clinical Veterinary Pharmacy I

CLIVEPHI

2

MPT 806

Clinical Practice Experience I

CLIPREXI

3

MPT 810

Clinical Practice Experience II

CLIPEXII

3

Elective Courses

MPT 808

Drugs and Vaccines Production and Development

DVAPRDEV

4

MPT 812

Clinical Practice Experience III

CLIPRIII

2

 

 

11.22.1  Course Synopses

MPT 801: Clinical Pharmacology (3 Credit Units)              

Pharmacodynamics and Pharmacokinetics: The actions and fate of drugs in the body; The physicochemical factors in transfer of drugs across membranes, drugs absorption, bioavailability, and routes of administrations, drug distribution, distribution into CNS, CSF and placental.  Drug Biotransformation, excretion clinical pharmacokinetics, half-liter.  Design and optimization of dosage regimen, loading dose, maintenance dose individualizing dosages mechanism of drug action, drug receptors.

 

MPT 802:  Veterinary Pharmaceutics (2 Credit Units)

The Pharmaceutical formulation of veterinary drugs and biologicals to maximize bioavailability and manufacturability. Choice of drugs and dosage, dosage forms, administration vehicles.  Frequency of administration, duration of treatment, drug interactions and adverse drug reactions in veterinary clinical practice.

 

MPT 803:   Veterinary Therapeutics (2 Credit Units)

Detailed discussion on the indications, uses and administration of veterinary labeled medications used in the treatment of diseases affecting animal patients.  Marketing and usage of various drugs in management of clinical conditions in veterinary practice, therapeutic drug monitoring.

Therapeutic incompatibility, dosage errors, wrong drugs of dosage form, contraindicated drugs, formation of toxic compounds and drug interactions.

 


MPT 804: Clinical Veterinary Pharmacy I (2 Credit Units)

Essentials of prescription writing, requirement for prescription writing; form of prescription order, handling of prescription, pricing of prescription, preparing prescription, packaging, delivering the prescription, recording of prescription, filling of prescription, prescription containers, prescription received.

 

MPT 805:  Clinical Veterinary Pharmacy II (3 Credit Units)

Requirement for compounding drugs of veterinary importance, dispensing medicaments; dispensing injections, lotions, ointment, emulsions, tablets, capsules boluses and biological, treatments in veterinary clinical practice.

 

MPT 806: Clinical Practice Experience I (Regulatory Issues in Veterinary Pharmacy)

(3 Credit Units)

Legal and regulatory issues that affect the practice of veterinary pharmacy will be emphasized.  (NAFDAC regulations in procurement, handling and marketing of veterinary drug, NAFDAC registration procedure for Veterinary Pharmaceuticals, Biologicals, Chemicals, pesticides and medical devices).  Pharmacy Act, the veterinary Surgeons Act, NAFDAC Act.  Compositions of membership of the various regulatory councils.

 

MPT 807:  Applied Biostatistics in Veterinary Science (2 Credit Units)

Introduction to biostatistics, introduction to epidemiology, statistical computing with SAS, research data coordination, analysis of categorical data, randomized clinical trials I, II, III.  Drug development from pharmaceutical perspective.

 

MPT 808:  Drug and Vaccines Production and Development        (4 Credit Units)

Historical background, drug and vaccine targets, screening and design, Nature as source of drugs; plant-derived microbial metabolites, marine invertebrates.  Chemical diversity of natural products, natural products discovery; screening structural elucidation.   Guidelines for investigation of new drugs, new drug application process.

 

Vaccine development, testing and regulation, government oversight, stages of vaccine development and testing (explorative stage, pre-clinical stage).  Clinical studies with human subjects Phase I, II, III of vaccine trials.  Approval and licensure, Post licensure monitoring of vaccine.

 

 

 

MPT 810: Clinical Practice Experience II (Clinics in Veterinary Pharmacy, Pharmacology and Therapeutics )         (3 Credit Units)

A bi-weekly regular clinical rounds with consultants in clinical pharmacy and therapeutic and consultants in veterinary medicines for assessing the choice of drugs, relevance, activities, mechanisms and adverse drug reactions of commonly used drugs and medicaments in veterinary clinical practice in Nigeria.

 

MPT 812:  Clinical Practice Experience III (Veterinary Business and Management)          

(2 Credit Units)

An overview of demand and supply of veterinary drugs and services in Nigeria; Types and description of Veterinary business and ventures till date; Business in

variety of food animal practices/businesses 

companion, sports and security animal practice/business; and

animal feed business.  Practice management techniques; capital equipment and staff requirements; financial management in Veterinary business; keys to efficiency and job satisfaction.

 

MPT 889:  Project (3 Credit Units)

Research project in areas of veterinary pharmacy, pharmacology and therapeutics.

 

 

11.22.2  Postgraduate Lecturers

Staff Name

Rank

Qualifications

Specialty

Arowolo, R.O.A.

Professor

DVM, M.Sc., Ph.D, FCVSN

Veterinary Pharmacology and Therapeutics

Otesile, E. B.

Professor

DVM, MVM, Ph.D, FCVSN

Veterinary Medicine and Surgery

Dipeolu M.  A.

Professor

DVM, MVPH. Ph.D, FCVSN

Veterinary Public health

Olukunle, J. O.

Senior Lecturer

DVM, M.Sc., Ph.D, FCVSN

Veterinary Pharmacology and Therapeutics

Adenubi, O. T.

Lecturer I

DVM, M.Sc

Veterinary Pharmacology and Therapeutics

Saba, A. B.

Senior Lecturer

(Associate Lecturer)

DVM, M.Sc., PhD

Veterinary Pharmacology and Therapeutics

Adeyemi, S. O.

Adjunct Lecturer

B. Pharm, LLB, DVM, MBA, MVPM, PhD

Veterinary Pharmacy and Jurisprudence

Agbato O.

Adjunct Lecturer

DVM, MBA, FCVSN

Veterinary Pharmacy and Business Management

Oyewusi J. A.

Adjunct Lecturer

DVM, M.Sc.

Veterinary Pharmacology and Therapeutics


11.23     BIOCHEMISTRY UNIT

11.23.1  Master of Science (M.Sc) in Veterinary Biochemistry

Admission Requirements

Master of Science in Veterinary Physiology is open to:

Graduates of Veterinary Medicine of FUNAAB and other Institutions recognized by Senate

Any other qualifications that are equivalent to FUNAAB’s DVM Degree

Graduates of Biological Sciences of FUNAAB and other Institutions recognized by Senate.

Fellows of the Nigerian Institute of Medical Laboratory Science or its equivalent.

Duration of Programme

The duration of the study for the Masters Programme shall be a minimum of four Semesters and a maximum of eight Semesters for full time candidates; while part time studies shall be for a minimum of six Semesters and a maximum of ten Semesters.

Graduation Requirements

The final assessment shall be undertaken only when all courses and project requirements for the degree have been fulfilled and certified by the Supervisors.

 

 

POSTGRADUATE COURSES FOR VETERINARY BIOCHEMISTRY

 

First Semester Courses

Course Code

Course Title

Abbreviation

Unit

Compulsory Courses

VCM 801

Developments in Veterinary Science

DEVVETSC

1

CSC 801

Use of Computer in Research

USEOCOMP

4

VCH 803

Biostatistics in Veterinary Science

VETBIOSC

3

VPM 801

Applied Immunology

APLDIMMU

2

VCM 803

Research Ethics

RESETHIC

1

VBB 811

Veterinary General Biochemistry

VEGENBIC

3

VBB 813

Methods of Biochemical Analysis

MTOBIANA

3

VBB 897

Seminar I

SEMINARI

1

VBB 899

Dissertation

DISSERTN

6

Elective Courses

VBB 815

Veterinary Nutritional Biochemistry

VENUTBIC

2

VBB 817

Veterinary Biochemical Toxicology

VEBIOTOX

2

 


Second Semester Courses

Course Code

Course Title

Abbreviation

Unit

Compulsory Courses

VBB 812

Clinical Biochemistry

CLINIBIC

3

VBB 818

Enzymology and Protein Chemistry

ENZPRCHE

3

VBB 820

Veterinary Molecular Biotechnology

VEMOLBIO

3

VBB 898

Seminar II

SEMINAII

1

Elective Courses

VBB 814

Endocrine and Blood Biochemistry

ENDBLBIC

2

VBB 816

Biochemistry of Carbohydrates and Lipids

BICHOLPD

2

 

11.23.2  Doctor of Philosophy (Ph.D) Programme in Veterinary Biochemistry

1.            Master degree from FUNAAB or any other University recognized by Senate

2.            Any other qualification adjudged to be equivalent to a masters degree.

Admission Requirements

Master of Science in Veterinary Physiology is open to:

Graduates of Veterinary Medicine of FUNAAB and other Institutions recognized by Senate

Any other qualifications that the Senate approves as equivalent to FUNAAB’s DVM Degree

Graduates of Biological Sciences of FUNAAB and other Institutions recognized by Senate.

Fellows of the Nigerian Institute of Medical Laboratory Science or its equivalent.

Graduation Requirements

The final assessment shall be undertaken only when all courses and project requirements for the degree have been fulfilled and certified by the Supervisors.

 

Doctor of Philosophy (Ph.D) Course

Course Code

Course Title

Abbreviation

Unit

VBB 997

Thesis Seminar (Pre-data Seminar)

PREDATA

1

VBB 998

Thesis Seminar (Post-data Seminar)

POSTDATA

1

VBB 999

Thesis

RETHESIS

6

 


11.23.3  Course synopsis

VBB 811: Veterinary General Biochemistry (3 Credit units)

Review of Carbohydrates, proteins, lipids and nucleic acid metabolism in animals and their regulation, Generation of ATP, Inter-relationship of metabolic pathways, medical and biological importance of carbohydrates, proteins, lipids and nucleic acids, classifications of carbohydrates oxidation and respiratory chain, integration of carbohydrate, lipid and protein metabolism.

 

VBB 812: Clinical Biochemistry  (3 Credit units)

Evaluation of liver, kidney etc function test, enzymes of clinical importance, molecular basis of in born errors of metabolism, classical examples of disease associated with carbohydrates, amino acids, lipids and nucleic acid metabolism.

 

VBB 813: Methods of Biochemical Analysis (3 Credit units)

Review of basis techniques, Buffer and PH, Principals of centrifugation, use of marker enzymes, spectrophotometer Electrophoresis, Isolation of enzymes, Chromatography, Studies of properties of enzymes, methods for estimation of blood constituents by colorimetric methods.  Colorimetric methods for blood glucose estimation, Auto-analyzer, serum calcium estimation by spectrophotometric method, Determination of urine constituent, nitrogenous organic compounds of urine, in organic constituent of abnormal urine, reducing sugars in urine.

VBB 814: Endocrine and Blood Biochemistry (2 Credit units)

Blood, plasma and serum, structure of erythrocyte membrane, white blood cells, platelets, other organic compound or constituent of blood.   Hormones of clinical importance, Insulin, glucagon, glucocorticoid, mineralocorticoids etc.

 

VBB 815: Veterinary Nutritional Biochemistry (2 Credit units)

Nutrients metabolism, nutrients requirements allowances, disorders associated with inadequate and excessive nutrients intake, environmental toxicants in food, vitamins and minerals, water electrolytes and acid base balances, energy, nutrients, medicines and toxins of food, ruminant biochemistry.

 

VBB 816: Biochemistry of carbohydrates and Lipids (2 Credit units)

Metabolism of carbohydrates and lipids, integration of metabolism of both carbohydrate and lipids, gluconeogenesis, glycogenolysis, cholesterol, lipoproteins, membrane lipids, glycolipids.

 

VBB 817: Veterinary Biochemical Toxicology (3 Credit units)

Detoxification of xenobiotics, Biochemistry of apoptosis, organ function tests, toxicology of drugs, chemical pesticides, insecticides, mode of action of toxins, carcinogenesis, environmental toxicology.

 

VBB 818: Enzymology and Protein Chemistry (3 Credit units)

Amino acids and peptides, proteins, protein structure. Determination of protein structure, Denaturation of proteins, plasma proteins, acute phase proteins, immunoglobulin’s, immunoglobulin’s disorders, enzyme inhibition, enzyme regulation, enzyme kinetics.

 

VBB 820: Veterinary Molecular Biotechnology (3 Credit units)

Nucleotides, nucleotide metabolism, nucleic acids, biosynthesis of nucleic acids, recombinant DNA technology.  Cloning, stem cells, Gene targeting, different steps of recombinant DNA technology that is used to obtain a gene product, vectors used in gene therapy.

 

VBB 897: Thesis Seminar I (Pre-data Seminar)    (1 Credit units)

This is essentially a pre-data seminar on the research focus of the student’s projects covering the title, objective and scope of the work, review of relevant literature, experimental design and methodology.

VBB 898: Thesis seminar II (Post-data Seminar) (1 Credit units)

This is a follow-up seminar/post-data or bench work findings.  It should cover research findings, detailed analysis and interpretation of research results, discussion of findings in view of previous reports and new ideas emanating from the study, conclusion and recommendations for future work.

11.23.4  Postgraduate Lecturers for Veterinary Biochemistry

Staff Name

Rank

Qualifications

Specialty

Dr. L. A. Durotoye

Senior Lecturer

DVM, M.Sc, Ph.D

Veterinary Physiology & Biochemistry

* Ola-Davies, O. E.

Senior Lecturer

DVM, M.Sc, Ph.D

Veterinary Biochemistry

Okediran, B.S.

Lecturer I

B.Sc (Biochemistry), DVM, M.Sc, P.hD

Veterinary Biochemistry

Thomas, C. F.

Lecturer I

 DVM, M.Sc

Veterinary Biochemistry

*  Associate Lecturer

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